Phenytoin definition
Web17. feb 2024 · Phenytoin may produce falsely low results for serum concentrations of T 4 and T 3, and dexamethasone or metyrapone tests. Phenytoin may cause increased serum levels of thyroid-stimulating hormone (TSH; usually in the absence of clinical hypothyroidism). Adverse Reactions. Frequency not defined: Webdiphenylhydantoin: [ fen´ĭ-toin″ ] an anticonvulsant used in the treatment of epilepsy other than the petit mal type, the treatment of status epilepticus , and the prevention and treatment of seizures associated with neurosurgery; administered orally. Called also diphenylhydantoin .
Phenytoin definition
Did you know?
Web20. dec 2024 · Phenytoin is a drug that is used to control seizures and it is generally used as an anticonvulsant or antiepileptic drug. The drug is also known by other brand names like Dilantin or Eptoin. It works by slowing down the impulses in the brain and minimizing the activity of brain stem centers. Phenytoin also acts as an anti-arrhythmic and a ... Web6. júl 2024 · definition of status epilepticus. The definition of status epilepticus has evolved considerably over the past two decades, leading to some inconsistencies. ... Free phenytoin levels are the ideal parameter to follow, since this reflects the active drug concentration. The target free phenytoin level is 1-2 ug/mL.
Web15. jan 2024 · Phenytoin is a Vaughn Williams Class IB antiarrhythmic; although, it is almost never used as an antiarrhythmic anymore. Its effects on the cardiac voltage-gated sodium channels can lead to dysrhythmias as well as SA and AV nodal blocks although such effects have rarely been reported following ingestion of the oral form. WebPhenytoin is classified as an antiarrhythmic and can cause SA and AV nodal blocks as well as dysrhythmias due to its effect on voltage-gated sodium channels. 3 Further, since phenytoin is poorly soluble, the parenteral form is administered with propylene glycol, which is a cardiac depressant. 3 The infusion rate of parenteral phenytoin should ...
WebPhenytoin /fəˈnɪtoʊɨn/ is a hydantoin-derivative anticonvulsant drug used primarily in the management of complex partial seizures and generalized tonic-clonic seizures. Phenytoin is also used to prevent seizures following neurosurgery. Phenytoin is believed to protect against seizures by causing voltage-dependent block of voltage-gated sodium channels. WebPhenytoin (Dilantin) Correction for Albumin / Renal Failure Corrects serum phenytoin level for renal failure and/or hypoalbuminemia. INSTRUCTIONS Use in patients with albumin ≤3.2 g/dL (32 g/L). The “Sheiner-Tozer Equation” is the official name of this correction.
WebThe meaning of PHENYTOIN is a crystalline anticonvulsant compound C15H12N2O2 used in the form of its sodium salt in the treatment of epilepsy —called also diphenylhydantoin. a crystalline anticonvulsant compound C15H12N2O2 used in the form of its sodium salt in the treatment of epilepsy —called also diphenylhydantoin…
WebStevens-Johnson syndrome is a rare side effect of phenytoin. It causes flu-like symptoms, followed by a red or purple rash that spreads and forms blisters. The affected skin eventually dies and peels off. It's more likely to happen in the first 8 weeks of starting phenytoin, or when the dose is increased too quickly. blood cultures are performed to test forWebnoun A crystalline compound, C 15 H 11 N 2 O 2, used as an anticonvulsant. Webster's New World Similar definitions (medicine) An anticonvulsant drug, 5,5-diphenylimidazolidine-2,4-dione, used in the treatment of epilepsy. Wiktionary Synonyms: dilantin diphenylhydantoin Advertisement Other Word Forms of Phenytoin Noun Singular: phenytoin Plural: free cookery classes onlineWebFosphenytoin (Cerebyx, Parke-Davis; Prodilantin, Pfizer Holding France [1]) is a water-soluble phenytoin prodrug used only in hospitals for the treatment of epileptic seizures. On 18 November 2004, Sicor (a subsidiary of Teva ) received a tentative approval letter from the United States Food and Drug Administration for a generic version of ... blood cultures which bottle to draw firsthttp://dictionary.sensagent.com/Fosphenytoin/en-en/ blood cultures times 2WebPhenytoin, a widely used antiepileptic drug, has a narrow therapeutic index and large inter-patient variability, partly due to CYP2C9 genetic variation. Patients with the CYP2C9 poor metabolizer phenotype may require reduced doses of phenytoin. Additionally, the HLA-B*15:02 variant is associated with an increased risk of phenytoin-induced cutaneous … blood cultures testWeb1. máj 2014 · Mean plasma half life of phenytoin is similar whether . given orally or IV. [15] In this study IV administration . of phenytoin led to more toxicity although drug levels . blood curdling definitionWeb30. jún 2015 · Phenytoin is the classical poster child for non-linear elimination kinetics, because the enzyme saturation point is reached somewhere in the middle of the therapeutic concentration range. free cookie banner for website