WebApr 9, 2024 · Clopidogrel (Plavix®) is a widely used anti-platelet agent that is commonly combined with aspirin to reduce the risk of various cardiovascular events. Because of the associated increased risk of gastrointestinal bleeding with this combination, a proton pump inhibitor (PPI) is often prescribed during such therapy. WebConclusion: The combination use of clopidogrel and certain types of PPIs (omeprazole, lansoprazole, esomeprazole, pantoprazole) increases the risk of MACE in patients with …
Combination Use of Clopidogrel and Proton Pump Inhibitors
WebMar 31, 2024 · How to take Plavix (Clopidogrel)? Use Plavix (Clopidogrel) exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller … WebApplies to: omeprazole and Plavix (clopidogrel) Talk to your doctor before using clopidogrel together with omeprazole. Combining these medications may reduce the effectiveness … first winter classic game
can i take omeprazole with plavix - MedHelp
If possible, it is recommended to avoid taking Plavix and omeprazole together. If a PPI (proton pump inhibitor) must be used, Protonix (pantoprazole) seems to be the least likely to cause a significant interaction (a study published in the American Heart Journal discusses this). See more Plavix is a prodrug, meaning that it must be metabolized in the body to its active form. It is inactiveuntil it is transformed. In most cases, a liver enzyme is what … See more The evidence for the interaction is so overwhelming, the FDA published labeling changes in the prescribing information for Plavix warning … See more There have been many, many studies looking into the potential interaction between Plavix and omeprazole (and PPI drugs in general). Most have shown that there isa clinically significant interaction, with a real world … See more WebApr 1, 2024 · If you are also taking omeprazole (Prilosec®) or esomeprazole (Nexium®), do not use it at the same time that you take this medicine. Talk with your doctor about using a different antacid. Your doctor may tell you to take aspirin while you are using clopidogrel. Do not change the dose or stop taking the aspirin without talking to your doctor first. http://www.clotcare.com/clopidogrelprotonpumpinhibitors.aspx first winter classic at fenway